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T1-weighted,contrast- enhanced sagittal (a) and axial (b) MRI scans of a sizable intramedul- lary angioblastoma at Th6Th7 in a 47-year-old woman. Palaeobiology as a discipline emerged out of a conviction that macro-evolution requires specific causal theo- ries and modes of explanation which, while compatible with micro- evolutionary processes, cannot be reduced to them. And concentration of the substance being determined. Why think of fitness in this way rather than as having a longer time horizon.

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